Dr Nicola J Patron
The Earlham Institute
Norwich Research Park
PhD Studentship: Design Principles for Synthetic Gene Regulation
Funding: Norwich Research Park Doctoral Training Partnership
This project aims to identify and characterise conserved plant cis-regulatory elements. It will employ a synthetic biology approach, using comparative analyses of genomic datasets to inform iterative ‘design-build-test-learn’ engineering cycles. These will test hypotheses on the relationship between sequence and function and develop minimal synthetic regulatory elements for use in plant biotechnology. The student will acquire skills in bioinformatics, comparative genomics and molecular biology.
The Earlham Institute specialises in genomics technologies and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing.
The Institute is located on the Norwich Research Park (NRP) which has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health. Set in over 230 hectares of parkland, the Norwich Research Park is a thriving community of several research institutes over 40 businesses, 3,000 scientists, researchers and clinicians.
Norwich is the capital of East Anglia. A cathedral city on the River Wensum, it retains many of its medieval structures, including the Norwich Lanes, parts of the ancient city walls and a wealth of historic buildings. The Norman Cathedral has magnificent Cloisters and a large Cathedral Close. The Castle has a 12th century keep prominently overlooking the city. Norwich is England’s first UNESCO city of literature and hosts a large arts festival and several beer festivals. The spectacular North Norfolk Coast and the Norfolk Broads National Park are both easily accessible from the city.