Our Research

AUTOMATED NANOSCALE DNA ASSEMBLY

The field of bioengineering is underpinned by our ability to assembly bespoke and complex DNA molecules at scale.  In 2015, we led the establishment of a common genetic syntax for the exchange of DNA parts for plants. We have also worked with the iGEM Foundation to introduce a PhytoBrick standard. We are working to push the limits of the size and scale of DNA assembly and have recently automated the fabrication of large DNA assemblies in sub-microliter volumes at the Earlham DNA Foundry. This has been coupled to validation using next-generation sequencing technologies.

People: Tony West, Oleg Raitskin
Collaborators: Earlham DNA Foundry, Liverpool GeneMill, Jim Haseloff (University of Cambridge), Fernan Federici (PUC, Chile)
Funding: BBSRC (BB/CCG1720/1)